Advances and Technical Standards in Neurosurgery by G. J. Pilkington, P. L. Lantos (auth.), L. Symon, L.

By G. J. Pilkington, P. L. Lantos (auth.), L. Symon, L. Calliauw, F. Cohadon, J. Lobo Antunes, F. Loew, H. Nornes, E. Pásztor, J. D. Pickard, A. J. Strong, M. G. Yaşargil (eds.)

As an addition to the eu postgraduate education approach for younger neurosurgeons we started to post in 1974 this sequence of Advances and Technical criteria in Neurosurgery which was once later backed by way of the eu organization of Neurosurgical Societies. This sequence used to be first mentioned in 1972 at a mixed assembly of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the sequence being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbiihl. hence have been proven the rules of ecu co­ operation that have been born from the ecu spirit, flourished within the eu organization, and feature all through been linked to this sequence. the truth that the English language is definitely to be able to changing into the foreign medium at ecu medical meetings is a brilliant asset when it comes to mutual knowing. as a result now we have determined to post all contributions in English, whatever the local language of the authors. All contributions are submitted to the total editorial board sooner than book of any quantity. Our sequence isn't really meant to compete with the guides of unique clinical papers in different neurosurgical journals. Our purpose is, fairly, to offer fields of neurosurgery and similar components within which vital contemporary advances were made. The contributions are written by means of spe­ cialists within the given fields and represent the 1st a part of each one volume.

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The main objective of this paper is to suggest that information that can be provided by simple histological techniques and integration of imaging and clinical data in the histological interpretation of gliomas has not yet been correctly and fully exploited. Historical Considerations The first attempts to classify gliomas were based on the observation that gliomas resemble the normal glia of mature brain tissue (Virchow 1864). Histoprognosis of Gliomas 45 Accordingly, gliomas have been categorized subsequently as astrocytomas, oligodendrogliomas and ependymomas.

3. Tumours of Uncertain Histogenesis Capillary Haemangioblastomas These tumours have been recently classified as tumours of uncertain origin, indeed the origin and role of the principal, so-called stromal cells in the formation of the neoplasm are controversial. 4% of all intracranial tumours (Ziilch 1986), they may occur at any age, but the peak incidence is in the fourth decade and develop most often in the cerebellum. Multiple lesions suggest Lindau's syndrome, a familial, inherited condition frequently associated Biological Markers for Tumours of the Brain 31 with angiomatosis of the retinae (von Hippel's disease).

However, scepticism was soon expressed concerning the efficacy of grading gliomas in general. The objections have been, and are still, most often based on the following (Ziilch et al. 1979): firstly, available sampling size: the tumour may display various degrees of histological malignancy in different areas; secondly, progressive evaluation over a period of months or years of an originally benign neoplasm to a more malignant one; thirdly, grading systems alone fail to take into account the topography of a tumour and age of the patient, factors which have been found consistently to affect clinical behaviour.

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